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Methylene Blue (MB)

Methylene Blue (MB), is a versatile compound with a spectrum of applications, from its traditional use as a biological stain and antidote to more cutting-edge medical treatments.

Widely recognized in histology and microbiology for its efficacy in staining tissues, methylene blue extends its impact beyond the laboratory. From it’s role as a crucial antidote for methemoglobinemia, a condition affecting blood oxygenation, to antioxidant, neuroprotective, antimicrobial, and anti-cancer properties, methylene blue is an old, new drug with many exciting possibilities.

Methylene Blue MB Capsules Prescription Rx Creative Scripts Compounding Pharmacy near me Naples Florida FL

Methylene Blue Capsules

Our pharmacists are experts in compounding Methylene Blue for patients suffering from a multitude of health conditions. 

Florida practitioners can easily prescribe Methylene Blue to Creative Scripts Pharmacy, with our guidance as needed, every step of the way. Connect today, to get started. Patients deserve the best.

Why Do Practitioners Prescribe Methylene Blue?

Antioxidant Properties

As an antioxidant, methylene blue scavenges free radicals and reduces oxidative stress. This property has potential applications in mitigating damage associated with various conditions, including ischemia-reperfusion injuries, cardiovascular diseases, long-COVID, and age-related disorders. Ongoing research is exploring how methylene blue’s antioxidant effects can be harnessed for therapeutic purposes.

Neuroprotective, Psychiatric, & Cognitive Potential Benefits

One of the most promising developments in methylene blue research is its potential as a neuroprotective agent. Studies have shown that methylene blue may have a positive impact on neurodegenerative diseases such as Alzheimer’s and Parkinson’s, as well as possibly improving cognitive performance and memory in patients without these conditions. The compound’s ability to enhance mitochondrial function and reduce oxidative stress in neurons has generated interest in its neuroprotective effects. It may also affect neurotransmitter systems, therefore having a positive impact on mood disorders such as depression and bipolar disorder.

Antimicrobial Properties

Methylene blue has demonstrated antimicrobial properties, making it a candidate for combating various infections. Researchers are exploring its potential as an alternative or adjunct therapy in the treatment of bacterial and fungal infections. The compound’s ability to inhibit the growth of microorganisms has sparked interest in its application in wound care and infectious disease management.

Anti-Cancer and Photodynamic Therapy

Preliminary studies suggest that the compound may have potential in cancer treatment by inhibiting tumor growth and inducing apoptosis (programmed cell death) in cancer cells. Future investigation aims to help reveal the mechanisms behind these anti-cancer effects and explore the compound’s role in combination therapies. Another method of cancer treatment is photodynamic therapy (PDT). PDT involves the administration of a photosensitizing agent, such as methylene blue, followed by exposure to light. This activates the compound, leading to the production of reactive oxygen species that can destroy targeted cells, including cancer cells. Researchers are refining and expanding the applications of methylene blue-based PDT for more precise and effective cancer treatments.

Custom Compounded Methylene Blue

Purity is critical with Methylene Blue

The stringent testing for purity with low heavy metal content in methylene blue is crucial. The safety and efficacy of the medication are contingent upon it’s purity. Many companies can provide methylene blue, but only ethical companies provide certificates of analysis (C of A) on every lot. In medical treatments, impurities or elevated levels of heavy metals pose health risks for patients, necessitating a commitment to high purity standards to guarantee patient safety and minimize adverse reactions. 

Here at Creative Scripts, we ONLY source methylene blue from PCCA, an international compounding pharmacy wholesaler which tests each lot and provides that documentation to ensure the highest quality medication.

Important Considerations:

• Dosage and Administration: The appropriate dosage of methylene blue depends on the treated condition. It is crucial to follow healthcare provider recommendations regarding dosage and administration. Toxicity may occur if dosing guidelines are not followed closely.

• Adverse Reactions: Methylene blue may have side effects like any medication. Common side effects include urine discoloration, agitation, nausea and vomiting, and dizziness / lightheadedness to name a few. Serious side effects are rare but can occur, emphasizing the importance of medical supervision. Contact your physician or pharmacist if you notice anything out of the ordinary when taking any medication.

• Drug Interactions: Avoid use with medications used to treat depression or other mental health conditions. Selective Serotonin Reuptake Inhibitors (SSRIs), Selective Norepinephrine Reuptake Inhibitors (SNRIs) and Monoamine Oxidase Inhibitors (MAOi’s) are examples of these types of medications. Methylene blue may interact with other medications as well. Patients should inform their healthcare provider of all their medications to avoid potential interactions.


Creative Scripts Compounding Pharmacy custom builds medication, one patient at a time.

We use the highest quality pharmaceutical-grade ingredients, state-of-the-art bases, equipment, and technology. Continual training on the newest techniques, advances in therapy, and regulations allows our pharmacists and technicians to provide the safest, most effective medications for you AND your pets. In addition to compounded medications, we offer pharmaceutical-grade nutritional supplements, health advice, and hormone consults. Doctors of Pharmacy (PharmD’s) Jerry and Lisa Meloche have served Naples and surrounding communities since 2005.

If you believe you, or your patients, could benefit from Methylene Blue, contact Creative Scripts Compounding Pharmacy to seek the advice of our team. We are prepared to provide patients with guidance to improve success so they can experience a better quality of life.

Is Methylene Blue right for you? Contact us and we will help guide you.